The U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) has provided resources and support for communities around the world to meet the challenges of the AIDS pandemic.  Globally, PEPFAR is on track to exceed its original commitment of $15 billion over five years (2004 – 2008), and by the end of fiscal year 2008, the American people will have invested $18.3 billion in the global fight against HIV and AIDS.  PEPFAR is an umbrella program that includes the Centers for Disease Control and Prevention (CDC), the United States Agency for International Development (USAID), Peace Corps, the Department of Labor (DOL), Health Resources Services Administration (HRSA) the Department of Defense (DOD) and the State Department.  All of these U.S. Government agencies work as one team to strategically support national plans.

The United States is proud to support Lesotho’s leadership in the global HIV/AIDS response. PEPFAR provides direct service delivery and technical assistance support in Lesotho to maximize the quality, coverage, and impact of the national HIV/AIDS response.

Working together with the Government of Lesotho, the Global Fund to Fight AIDS, Tuberculosis and Malaria, and other development partners, PEPFAR is aligning investments to scale up evidence-based interventions in the geographic areas and populations with the highest burden of HIV/AIDS – in line with PEPFAR 3.0 (PDF 1.2 MB) Lesotho is participating in the Accelerating Children’s HIV/AIDS Treatment (ACT) Initiative, a two-year effort to enable 300,000 more children living with HIV/AIDS to receive life-saving antiretroviral treatment (ART) across priority countries in sub-Saharan Africa. Specific priorities include

  • Saturating priority districts with HIV combination prevention activities with a focus on treatment retention and tuberculosis (TB)/HIV co-infection
  • Scaling up HIV testing and counseling, voluntary medical male circumcision, and prevention of mother-to-child HIV transmission (PMTCT) by supporting Option B+
  • Implementing activities to strengthen health information systems, supply chain management, HIV/AIDS-related surveillance, and laboratory systems
  • Fostering partnerships with all stakeholders through collaborative program planning, implementation, and monitoring

HIV/AIDS in Lesotho

Number of people living with HIV (all ages), 20142 310,000
Deaths due to AIDS (all ages), 20142 9,300
Number of orphans due to AIDS (0-17), 2014 74,000
Estimated antiretroviral coverage (adults ages 15+), 20142 36%
HIV-positive TB patients, 20144 74%
Estimated percentage of pregnant women living with HIV who receive antiretrovirals for PMTCT, 20142 72%

Saving Lives

In 2014, PEPFAR supported the following achievements in Lesotho:

  • Life-saving ART for 118,453 people
  • Testing and counseling for over 447,785 people
  • Care and support for 46,920 orphans and vulnerable children (OVC) affected by HIV/AIDS
  • ART for 7,494 pregnant women living with HIV to reduce the risk of mother-to-child transmission

Get the most up-to-date data on program results, expenditures, and planned funding at

PEPFAR Planned Funding in Lesotho, 2007-2014 (USD in Millions)5

















1. Office of the U.S. Global AIDS Coordinator and Health Diplomacy. (2014). PEPFAR 3.0 – Controlling the epidemic: Delivering on the promise of an AIDS-free generation. Washington, DC: Author.

2. UNAIDS. (2015). How AIDS changed everything. Geneva: Author.

3. UNAIDS. (2014). Lesotho. Retrieved August 12, 2015, from

4. World Health Organization. (2014). Tuberculosis country profile, Lesotho. Retrieved on May 21, 2015 from

5. Data reflect information available on the PEPFAR Dashboards, which represent planned new bilateral funding initially approved in the PEPFAR Country Operational Plans/Regional Operational Plans (COPs/ROPs) each fiscal year. As additional funding may be approved and made available after the initial COPs/ROPs submission, or to PEPFAR-supported countries that are not required to submit an annual COP/ROP, data on the Dashboards may not represent the final PEPFAR programmatic funding level in countries each fiscal year.